The Scientific Basis of the CANS-MCI Blog

  • Quick Download Links of Scientific Literature

    By on September 14, 2020

    This page collects in one place scientific literature regarding the CANS-MCI referred to in our other science-related blog posts. The purpose of this post is to give you quick access to published literature so you may download them in one place.

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  • Within-session Learning of an Object Identification Task Predicts Elevated Brain Aβ

    By on May 30, 2019

    In a multi-year study of 81 adults, conducted by the Kentucky Neuroscience Institute, the CANS-MCI has been shown to be sensitive to heightened CSF levels of Aβ and tau levels. The study examined cerebrospinal fluid (CSF) amyloid β 1-42 (Aβ) and tau levels and performance on a computerized self-administered test battery, the Computer-Administered Neuropsychological Screen for MCI (CANS-MCI).

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  • Sensitivity of the CANS-MCI to CSF Markers of Preclinical Alzheimer’s

    By on August 1, 2018

    In a multi-year study of 81 adults, conducted by the Kentucky Neuroscience Institute, the CANS-MCI has been shown to be sensitive to heightened CSF levels of Aβ and tau levels. The study examined cerebrospinal fluid (CSF) amyloid β 1-42 (Aβ) and tau levels and performance on a computerized self-administered test battery, the Computer-Administered Neuropsychological Screen for MCI (CANS-MCI).

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  • Scientific Background of the CANS-MCI

    By on December 7, 2017

    The CANS-MCI was developed to solve a problem: there were no tools available that could accurately and economically detect the cognitive changes most predictive of further abnormal decline in adults and the elderly.  The most common type of decline in need of early detection was toward Alzheimer’s disease.  Therefore the CANS-MCI was based upon a wide array of previous research concerning the changes most predictive of Alzheimer’s.

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  • Concerning Cognitive Testing over the Internet

    By on November 22, 2017

    Although the Internet may appear to give the advantage of availability and ease of access — especially to physically disabled people — the reliability of Internet test results is markedly affected by two detrimental human factors: distractions and coaching. Computer-administered tests should be given by a neutral tester in a controlled environment, preferably a designated quiet room in a medical facility.

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